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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T77574 | ROS inducer 1 | ROS , Antibiotic | |
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actini... | |||
T74225 | ROS-ERS inducer 1 | ||
ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reacti... | |||
T79517 | ROS inducer 2 | Reactive Oxygen Species | |
Compound I16 (ROS inducer 2) is a potent inducer of Reactive Oxygen Species (ROS) with an effective concentration (EC 50) of 3.43 μg/mL demonstrated in vitro. It exhibits exceptional bioactivity in vivo against Xanthomon... | |||
T79518 | ROS inducer 3 | Reactive Oxygen Species | |
Compound I6 (ROS inducer 3) is a potent ROS inducer with robust in vitro bioactivity, demonstrated by an EC50 of 2.86 μg/mL. It exhibits significant protective activity against Pseudomonas syringae pv. actinidiae, and as... | |||
T79252 | Apoptosis inducer 13 | Reactive Oxygen Species | |
Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion. Additionally, it facilitates the conversion of coenzyme NADH to NAD+, and elevates intracellular... | |||
T79639 | Lepadin H | Ferroptosis | |
Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lipid peroxidation. It simultaneously decreases SLC7A11 and GP... | |||
T81984 | Keap1-Nrf2-IN-10 | ||
Keap1-Nrf2-IN-10 (compound 15) is a potent inducer of NQO1 and efficaciously mitigates oxidative stress in gamma-irradiated mice by reducing MDA and ROS levels, as well as NQO1 in the liver, which enhances the survival r... | |||
T36514 | QD-394 | ||
QD-394 is an inducer of reactive oxygen species (ROS) production.1It induces lipid peroxidation, increases in intracellular accumulation of reactive oxygen species (ROS), and decreases in the reduced glutathione (GSH) to... | |||
T79777 | GPX4-IN-7 | Ferroptosis | |
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 μM. This compound ... | |||
T79359 | Anticancer agent 147 | Ferroptosis | |
Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS), and malondialdehyde (MDA), enhances endoplasmic reticulum ... | |||
T36882 | CAY10773 | ||
CAY10773 is a derivative of the ferroptosis inducer sorafenib .1It selectively inhibits proliferation of BEL-7402, MGC803, and T24 bladder cancer cells (IC50s = 5.77, 5.21 and 3.97 μM, respectively) over non-cancerous HC... |